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Topic 02Biology

A1.2 Nucleic acids

DNA and RNA store and transfer genetic information; their structure (nucleotides, antiparallel double helix, complementary base pairing) underpins faithful replication and expression.

Practice questions
1

Nucleotides and the polynucleotide backboneSign up

Components of a nucleotide · Phosphodiester bonds and 5′→3′ directionality

30 min
2

The double helix and base pairingSign up

Antiparallel strands & base pairing · DNA vs RNA & the universal code

30 min
3

Evidence for DNA as genetic material (AHL)HLSign up

Nucleosome packaging · Hershey-Chase experiment · Chargaff's rules & falsifiability

30 min

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